For those who discover any main omissions or other inaccuracies in the publication listing, make sure you let's know.
Our group experiments bacterial mobile division and is also aiming to constitute a ‘base up biology’ in synthetic cells that may autonomously divide. Our main desire lies in mobile division, chromatin construction, and spatial control.
[Laughs] ‘It was certainly an excellent danger! At the time, I had been perfectly aware that it could go Completely wrong Which I could turn into a lot less effective, but I just ignored that. Curiosity has normally been my strongest driving pressure. And by chance it all worked out.’
Since 2000, Dekker has shifted the principle focus of his perform to biophysics exactly where he reports the Attributes of single biomolecules and cells using the equipment of nanotechnology. This modification of field was driven by his fascination for your amazing performing of Organic molecular structures, along with via the long-phrase viewpoint that lots of appealing discoveries can be expected Within this discipline.[5] Recent traces of exploration in his biophysics group are while in the regions of:[6]
This yielded a breakthrough. Inside only some months, we had been ready to measure transportation by way of an individual one-walled carbon nanotube. Determined by small-temperature experiments by an excellent PhD university student in my group, Sander Tans (now a valued colleague and professor at Delft College of Technologies by having an active investigation lab at AMOLF in Amsterdam), we showed that carbon nanotubes have been legitimate quantum wires with really very long (micrometres) electronic coherence lengths — confirming theoretical predictions of metallic behaviour.
Electrical transportation in monolayers of phthalocyanine molecular wires and AFM imaging of just one wire bridging two electrodes
What distinguishes biology from chemistry is that these parts together make up a residing system. The key of said daily life, I think, lies while in the interactions, the interaction of Individuals molecules. The massive issue about the origin of lifetime is still unanswered. How did we ever evolve from very simple molecules in to the particularly complicated devices we see these days? We don't know. I need to operate on these kinds of massive, open up concerns.’
2011, to start with in vitro measurements of transportation throughout an individual biomimetic nuclear pore intricate; growth of multiplexed magnetic tweezers for kilo-molecule experiments; and settled the mechanism of homology recognition in DNA homologous recombination
2003, demonstrated the first biosensors built outside of a carbon nanotube; solved the construction and mechanism of DNA repair proteins; and discovery of a completely new system for fabricating stable-condition nanopores for DNA translocation
Bulk-area coupling identifies the mechanistic connection concerning Min-protein designs in vivo As well as in vitro
watch Share your interactive ePaper on all platforms and on your site with our embed function
In the meantime, to be certain ongoing assistance, we are exhibiting the website without models and JavaScript.
You are using a browser that won't supported by Fb, so we've redirected you to an easier Model to provide you with the very best experience.
Case in point (2) of bending configurations in 3D ceesdekker simulations of DNA rods on nanopores. A percentage of the membrane is proven in gray, the rim from the pore is highlighted in pink, as well as a 3D rendering of your motion with the DNA rod is displayed.